Chlorphenamine Totally Explained

Everything about Chlorphenamine totally explained

Chlorphenamine (INN) or chlorpheniramine (USAN, former BAN), commonly marketed as its salt chlorphenamine maleate (CPM; Chlor-Trimeton, Piriton, Chlor-Tripolon), is a first-generation alkylamine antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorpheniramine is one of the most commonly used antihistamines in small-animal veterinary practice as well.
   Chlorpheniramine is part of a series of antihistamines including pheniramine (Naphcon) and its halogenated derivatives and others including fluorpheniramine, dexchlorpheniramine (Polaramine), brompheniramine (Dimetapp), dexbrompheniramine (Drixoral) deschlorpheniramine, dipheniramine (also known as triprolidine with the trade name Actifed) iodopheniramine &c.
   The halogenated alkylamine antihistamines all exhibit optic isomerism and chlorpheniramine in the indicated products is racemic chlorpheniramine maleate whereas dexchlorpheniramine (Polaramine) is the dextrorotary (right-handed) stereoisomer.
   Also known as "Comakin" in Taiwan and parts of Asia.

Combination medications

Chlorpheniramine is often combined with phenylpropanolamine to form an allergy medication with both antihistamine and decongestant properties. Brand names include Demazin, Allerest 12 Hour, Chlornade, Contac 12 Hour, A. R. M. Allergy Relief, Ordrine, Ornade Spansules, Teldrin, and Triaminic.

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